Biomedical Engineering Reference
In-Depth Information
Figure 40.1.
Aconcept of tissue engineering and regenerative medicine.
and can be cultured in the laboratory. They are multipotent
and show active proliferation.
8
One of the TERM approaches has
attempted to create new bone based on MSCs seeded onto porous
ceramic scaffolds. The scaffolds in TERM also play an important
role and the ideal biomaterial scaffolds, particularly in bone
regeneration fields with complicated bone defect shapes, should
have excellent plasticity for fitting into complex defect shapes, and
the rate of absorption needs to be fast in order to avoid infection.
Therefore in this chapter, we would show the possibility of applying
biodegradable scaffoldsfor boneregeneration.
40.2 Biodegradable Scaffolds
40.2.1
Biodegradable Ceramic Composite (
β
-TCP)
Nonbiodegradable scaffolds such as a ceramic composite (hydrox-
yapatite [HA]) possess inherent problems, including infection,
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