Biomedical Engineering Reference
In-Depth Information
Chapter 39
APPLICATION OF SCAFFOLDS FOR
ARTIFICIAL SKIN IN REGENERATIVE
MEDICINE
Hyun Ju Lim
a
and Ho Yun Chung
b
a
Department of Advanced Organic Materials Science and Engineering, Kyungpook
National University, 1370 Sankyuk-dong, Buk-gu, Daegu, Republic of Korea
b
Department of Plastic & Reconstructive Surgery, Kyungpook National University,
School of Medicine, 50, Samduck-dong, Joong-gu, Daegu, Republic of Korea
witchzz@hanmail.net; hy-chung@knu.ac.kr
Tissue engineering and regenerative medicine is a rapidly grow-
ing and emerging as an interdisciplinary field in the area of bio-
logical and medical cooperation, which aims to regenerate new
biological material for replacing diseased or damaged tissues or
organs. Tissue engineering for skin, as the largest organ of the
human body, has been developed from early periods. Nowadays,
skin is readily accessible for direct tissue modulation, for exam-
ple, gene therapy or stem cell therapy. And many researchers are
approaching to replace scar or nonfunctional tissue using biologi-
cal scaffolds for skin regeneration, such as collagen, gelatin, fibrin
glue, chitosan, poly(lactic acid) (PLA), poly(lactic-co-glycolic acid)
(PLGA),andsoon.Furthermore,manytissue-engineeredproducts
areshowing,suchasEpicel
R
,Integra
R
,Alloderm
R
,Transcyte
R
,
Apligraf
R
, and so on. And theirclinical applications are reported.
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