SCAFFOLD CONSIDERATIONS FOR OSTEOCHONDRAL TISSUE ENGINEERING - Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine - page 784

oriented perpendicular to the surface. The aggrecan concentration
and compressive strength increase by an order of magnitude across
the depth of the cartilage from the surface to the deep zone. The
superficial zone is where cell density is the highest (Fig. 38.1).
Figure 38.1. Histology of immature bovine cartilage showing the transi-
tions from superficial- to deep-zone cartilage, the calcified cartilage layer,
and the underlying bone.