Biomedical Engineering Reference
In-Depth Information
Figure 30.4. Pore size distributions of cylindrical scaffold sections along
the longitudinal direction. (a) Alginate, (b) chitosan, and (c) PCL scaffolds
( n = 3) (Ref.22).
for five minutes, the pore size and porosity ranges in the prepared
scaffold along the cylindrical axis were observed from 80 88 μ m
to 310 405 μ m (Fig. 30.4) and from 80% 83% to 93% 94%
(Fig. 30.5), respectively, depending on the polymers used. The pore
size ranges could be also controlled by adjusting centrifugal speed;
for example, 180 325 μ m for 1,000 rpm and 135 290 μ mfor
2,000 rpm were observedfor the alginate scaffold(not shown).
30.3.2 Measurements of Mechanical Properties
Themechanicalpropertiesofthescaffoldsections(thickness5mm)
were measured by a biaxial tensile test equipment designed by
our laboratory for small scaffold samples, which was attached in
an Instron machine (AG-5000G, Shimadzu, Japan) with a 50 kg f
load cell. 27 A rod with a ball-shaped (diameter 6 mm) tip was
hammered vertically at a crosshead speed of 1 mm/min on the
Figure 30.5. Porosity distributions of cylindrical scaffold sections along
the longitudinal direction. (a) Alginate, (b) chitosan, and (c) PCL scaffolds
( n
=
3) (Ref.22).
 
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