Biomedical Engineering Reference
In-Depth Information
granule-type artificial bones are manufactured by pulverizing
porous block-type artificial bones, and therefore the size and shape
of the artificial bones are heterogeneous. This heterogeneity in size
and shape leads to heterogeneous spatial packing in the aggregate
and consequent generation of mechanically and biologically delete-
rious dead space. By fabricating the granules of the same size and
shapebyinjectionmolding,wehavediscoveredthattheseproblems
can be solved. The details will be published elsewhere in the near
future.
Acknowledgments
ThisworkwassupportedbyGrant-in-AidforScientificResearch(A)
#20240043fromtheJapanSocietyforthePromotionofScienceand
by Terumo Life Science Foundation.
References
1. R.P.Lanza,R.Langer,andJ.Vacanti,Eds., Principles of Tissue Engineering
(AcademicPress, San Diego, 2000).
2. L.Moroni,J.R.deWijn,andC.A.vanBlitterswijk, J. Biomater. Sci. Polym.
Ed. , 19 (5),543 (2008).
3. S. W. Herrin and, P. Ochareon, Orthod. Craniofac. Res. , 8 ,174 (2005).
4. P. Tessier, H. Kawamoto, D. Matthews, J. Posnick, Y. Raulo, J. F. Tulasne,
and S. A. Wolfe, Plast. Reconstr. Surg. , 116 ,6S(2005).
5. B.L.Eppley,W.S.Pietrzak,andM.W.Blanton, J. Craniofac. Surg. , 16 ,981
(2005).
6. M. Hallman and A. Thor, Periodontology , 47 ,172 (2008).
7. M.Hatoko,H.Tada,A.Tanaka,S.Yurugi,K.Niitsuma,andH.Iioka, J. Cran-
iofac. Surg. , 16 ,327 (2005).
8. S.Tomita,S.Molloy,L.E.Jasper,M.Abe,andS.M.Belkoff, Spine , 29 ,1203
(2004).
9. S. V. Dorozhkin and M. Epple, Angew. Chem. Int. Ed. Engl. , 41 , 3130
(2002).
10. E. Fischer-Brandies and E. Dielert, J. Oral Implantol. , 12 ,40 (1985).
11. B.L.Eppley, J. Craniofac. Surg. , 13 ,650 (2002).
 
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