Biomedical Engineering Reference
In-Depth Information
Figure 26.1.
Pressure cross-sectional area relationship of each material.
Polytetrafluoroethylene (PTFE) (
) showed a noncompliant response and
almost no change in the cross-sectional area in response to intraluminal
pressure. Canine common carotid artery (CCA) (
•
) and decellularized CCA
(DCCA) (
) exhibited compliant responses, in a so-called J-shaped curve.
Elastin gel combined with polylactic acid nanofiber tube (E-PLA) (
◦
)evi-
dencedcross-sectionalareachangesinresponsetoanincreaseofintralumi-
nal pressure, although the differences were relatively small compared with
that of CCA, DCCA, or decellularized canine ureter (D.Ureter) D.Ureter (
×
)
also showedacompliantresponse marked bymore distensibilityatalower
pressure range than CCA. and DCCA. Cross-sectional areas are expressed as
mean values
±
standard deviations(from Ref. 2, Murase
et al
., 2006).
available materials is still not satisfactory (Fig. 26.1).
2
In order to
overcome these di
culties, various approaches, including our own,
are described.
Bone tissue engineering has been widely tested in the fields of
orthopedic and oral surgery and has already been applied in clin-
ics. In particular, regeneration of alveolar bone for dental implant
surgery has attracted much attention since only a small volume of
regenerated bone is required in most of the cases, which is advan-
tageous in tissue engineering, and there is an increasing demand
by elderly patients for dental implant surgery. Currently, animal-
derived bioartificial bone substitutes have been widely used, but
riskssuchasinfectionandimmunoreactionsagainstanimal-derived
proteins have not been completely eliminated. Although the use of
Search WWH ::
Custom Search