Biomedical Engineering Reference
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transplanted cells. Apoptotic activity of ASCs cultured on macro-
porous PLGA microspheres was lower than that of trypsinized
ASCs. The implantation of ASCs cultured on macroporous PLGA
microspheres resulted in much more extensive adipose tissue for-
mationthantheimplantationofASCsculturedonplates,trypsinized,
and subsequently mixed with macroporous PLGA microspheres.
This method could be applied for adipose tissue augmentation or
reconstruction in plastic and reconstructive surgery.
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