Biomedical Engineering Reference
In-Depth Information
Figure 1.1.
Tissue engineering triad. Combining three key elements such
as cells, biomaterials, and signaling molecules, tissue-engineered neo-
organs would be regenerated.
can be applied to manufacture theoretically almost all organs and
tissues exceptseveral kindsof organs, like the brain.
1.2 Biomaterials for Regenerative Medicine
and Tissue Engineering
1.2.1
Importance of Scaffold Matrices in Regenerative
Medicine and Tissue Engineering
Scaffoldsmightplayaverycriticalroleinregenerativemedicineand
tissue engineering. The function of scaffolds is to direct the growth
ofcellsseededwithintheporousstructureofthescaffoldsorofcells
migrating from surrounding tissue. The majority of mammalian cell
types are anchorage dependent, resulting in dying if an adhesion
substrate is not provided. Scaffold matrices can be used to achieve
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