SYNTHETIC/NATURAL HYBRID SCAFFOLD FOR TISSUE REGENERATION - Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine - page 317

experiment, the fibrin/PLGA constructs exhibited good-quality
cartilage-like tissue compared withthe PLGA group.
We analyzed collagen type II and type I immunolocalization of
the fibrin/PLGA hybrid construct. Collagen type II was detected in
allspecimens.AsshowninFig.16.3,collagentypeIIexhibitedstrong

Collagen type II Collagen type I

1 wks

2 wks

4 wks

Figure 16.3. Collagen type II was detected in all in vitro specimens and at
eachtimepointof1,2,and4weekspostimplantation.SeealsoColorInsert.