Biomedical Engineering Reference
In-Depth Information
Chapter 14
TISSUE ENGINEERING
Hae-Won Kim
Department of Nanobiomedical Science & WCU Research Center,
Graduate School Dankook University, South Korea
Department of Biomaterials Science, School of Dentistry & Institute of Tissue
Regeneration Engineering (ITREN), Dankook University, South Korea
kimhw@dku.edu
Nanofibrous matrices made of medical-graded materials have
shown great potential for the regeneration of a variety of tissues,
includingbone.Theextremelyhighsurfaceareawithtunablefiber
diameters and compositions is attractive for alluring initial cellu-
lar events and stimulating development into specific tissue types.
Thischapterintroducesrecentstudiesonnanofibertechnologyfor
bone tissue engineering, with particular emphasis on the electro-
spinning approach. Generation of a bone-mimicking composition
and functionalization of matrices with bioactive factors are some
of the main focuses.
14.1 Introduction
Among the various types of scaffolds with three-dimensional (3D)
morphology to facilitate tissue development, the nanofibrous struc-
ture has recently gained great attention in the tissue engineering
Search WWH ::
Custom Search