Biomedical Engineering Reference
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Figure 13.10. Morphology of fibroblasts on (a) PHBV and (b) PHBV/
gelatin nanofibrous scaffolds for 1 d incubation (adapted from Ref. 17).
(Fig. 13.9c) and PHBV/gelatin scaffolds (Fig. 13.9d) comparison
withtheculturedish(Fig.13.9a)andthePHBVfilm(Fig.13.9b)after
4 hours of incubation. 4 , 8 NIH3T3 fibroblasts, cultured on PHBV and
PHBV/gelatin nanofibers for 1 day, are shown in Fig. 13.10. As the
results show, cells that adhered to the PHBV/gelatin scaffold (Fig.
13.10b)morequicklyformedamonolayercomparedwiththePHBV
nanofibrous scaffold (Fig. 13.10a), showing good tissue compatibil-
ity of the PHBV/gelatin nanofibrous scaffold. 17
Figure 13.11 shows cross-sectional images of the PHBV/gelatin
scaffold after fibroblast culture. After three days of incubation, a
monolayer morphology was found. After six days of incubation,
Figure 13.11. Cross-sectionalimagesofaPHBV/gelatinnanofibrousscaf-
fold after fibroblasts cultured after (a) 3 days and (b) 6 days incubation
(adapted from Ref. 17).
 
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