Biomedical Engineering Reference
In-Depth Information
Chapter 11
Jiang Chang,
a,b,*
Wenguo Cui,
b
Yue Zhou,
b
and Lei Chen
a
a
Biomaterials and Tissue Engineering Research Center, Shanghai Institute of Ceramics,
Chinese Academy of Sciences, Shanghai, 200050, Peoples Republic of China
b
School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong
University, 1954 Hua Shan Road, Shanghai 200030, People's Republic of China
*jchang@mail.sic.ac.cn
Electrospinning is one of the popular and preferred techniques
for the preparation of porous scaffolds which have great potential
in tissue engineering applications because of the similarity of the
structure of electrospun fibers to that of the extracellular matrix
(ECM). Many specific designs of electrospinning setups have been
developed to fabricate fibrous materials for different tissue engi-
neering applications. By modifying the electrospinning parame-
ters,fiberswithdifferentmorphologies,diameters,andstructures
can be fabricated. Nanofibers can be bundled to improve their
mechanical strength. Electrospun porous mats with different
two-dimensional (2D) patterned architectures can be fabricated
by designing electroconductive collectors with patterned struc-
tures. In addition, fibrous tubes with different macroscopic
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