GUIDANCE OF CELL ADHESION,ALIGNMENT, INFILTRATION, AND DIFFERENTIATION ON ELECTROSPUN NANOFIBROUS SCAFFOLDS - Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine - page 213

Table 10.2. Cellular interaction of various cell types with electrospun nanofibrous substrates.

Cell types Materials Fiber configuration Outcomes Reference

Mesenchymalstem cells PEUU Fiber diameter and alignment Ligament-like celldifferentiation 38

PLA Fiber alignment Cell alignment and in vivo differentiation 45

PCL Fiber alignment Chondrogenic differentiation 46

Collagen Fiber diameter Cell adhesion and differentiation 21

PCL, collagen, PES Randomly oriented fibers Hepatocyte-like celldifferentiation 47

PLLDO Randomly oriented fibers Cell adhesion and proliferation 16

Osteoprogenitor cell (MC3T3-E1) PLA Fiber diameter Cell spreading, proliferation, and differentiation 17

Embryonic stem cells PCL Fiber alignment Neuralcell differentiation 44

Skeletal musclecell PCL/collagen Fiber alignment Cell alignment and myotubeformation 22

C2C12 PU Fiber alignment, mechanical Cell alignment and maturation 48

and electrical stimulation

PEU Fiber alignment Cell adhesion and alignment 49,50

DRG PDO Fiber alignment Neuriteoutgrowth 51

PLA Fiber alignment Neuriteoutgrowth 52

DRG, Schwann cells, OEC, fibroblasts Collagen/PCL Fiber alignment Neuriteoutgrowth, celladhesion and migration 29

Schwann cells PCL Fiber alignment Cell maturation 32

Neural stem cells PES Fiber diameter Cell differentiation and proliferation 30

Fibroblasts PLGA Fiber diameter and orientation Cell adhesion and proliferation 38