Biomedical Engineering Reference
In-Depth Information
Figure 9.18.
Synthesis of methacrylated lactide HA63 (HEMA
=
2-
hydroxyethyl methacrylate, Me
=
methacrylate, LA
=
lactic acid, DMAP
=
dimethylaminopyridine, TEA
=
triethylamine, DCC
=
dicyclohexylcarbodi-
imide,TBA = tetrabutylammonium)
52
.
Mixing the Zn-HA solution and BDNF with His and a cross-linking
peptide with His at both termini (CLP), solutions turned automati-
cally into an HA hydrogel.
In situ
HA hydrogels by enzymes were fabricated by employ-
ing HA-tyramine (HA-Tyr) conjugates in the presence of hydrogen
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