Biomedical Engineering Reference
In-Depth Information
Figure 9.13.
Hydrogel formation via chemical reactions of HA and ADH
and subsequent coupling of bioactive drugs.
21
,
24
,
25
demonstrated significant reduction of both adhesion and inflamma-
tion in animals, indicating the effective prevention of postsurgical
adhesion by concurrent anti-adhesive drug delivery. This HA hydro-
gel was prepared by employing both HA-ADH and HA-aldehyde
(Fig. 9.14) through conjugations of ADH and sodium periodate,
respectively.Thisanti-inflammatoryfunctionofHAwasalsostudied
Figure 9.14.
Introduction of biotin to the HA backbone.
18
,
44
Search WWH ::
Custom Search