Biomedical Engineering Reference
In-Depth Information
Figure 6.3.
Fluorescence microscopic images of MC3T3-E1 cells in the
Tetronic-TA hydrogel by live/dead assay. The hydrogel formed with 0.25
wt% H
2
O
2
and (a) 0.6 mg/mL HRP; (b) 0.15 mg/mL HRP and 0.035 mg/mL
HRP; (c) the hydrogel formed with 0.6 mg/mL HRP; (d) 1 wt% H
2
O
2
;(e)
0.25 wt% H
2
O
2
; (f)0.063 wt%H
2
O
2
.
the Arg-Gly-Asp (RGD) peptide to the Tetronic hydrogel based on
theHRP-triggeringsystemwasdesignedtoexaminecelladhesionon
the hydrogels. The results showed that cell adhesion was enhanced
inanRGDconcentration-dependentmanner.Thesestudiesarenow
progressing to obtain adjusted physical and biological properties
as injectable biomaterials for a range of biomedical applications,
including tissueregeneration.
Figure 6.4.
Scheme of Tetronic/gelatin hydrogel catalyzed by HRP and
hydrogen peroxide. See also ColorInsert.
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