Biomedical Engineering Reference
In-Depth Information
research interest. Although DLC and heparin coatings are utilized for some of
the third generation commercial cardiac devices due to their excellent haemo-
compatibility, bioactive coatings on blood-contacting surfaces have been a topic
of intense research.
Endothelial cell (EC) lining on biomaterials is suggested for long-term
cardiac devices due to its antithrombotic properties (Scott-Burden et al., 1998).
A few attempts on the use of an EC lining to enhance the blood compatibility
can be seen in the literature (Wang et al., 2002; Sreerekha and Krishnan, 2006).
EC lining can be created on different materials with textured surface using in
vitro cell culture. Even though biological surface coatings seem to be promising
as a future technology compared with the current technology, they need further
development and investigation due to their possible lasting limitations.
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