b-Arrestins in the Immune System - Progress in Molecular Biology and Translational Science - page 374

increased phosphorylation, and 53 with decreased phosphorylation, which
represent a b -arrestin-mediated kinase-substrate network involved in a
number of cellular pathways. 176 However, the protein impact of b -arrestins
in the pathobiology of a variety of disease processes suggests efforts at devel-
oping agonists or antagonists will continue.
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