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For every combination
of 4 leads
One combination
of 4 leads
Calculate Standard
12-lead ECG
MECG
Caclulate PCs
PCs
Reconstructed
12-lead ECG
Target 12-
lead ECG
Calculate the similarity
between reconstructed and
target 12-leads ECGs
Similarity
measures
Similarity
factors
Find best similarity factor
Best similarity
factor
Find combination of 4
leads that resulted in the
best similarity factor
Optimal leads
Fig. 9.10 Optimal leads selection with principal component analysis (PCA)
DL
=−
X i
( )
X j
( ).
(9.26)
31
 =
For the MECG with 31 leads there are
465
possible differential leads.

2
However, in WSN applications, the implementation of a small wireless electrode,
whose measurement is emulated by DL, dictates the minimization of the distance
between electrodes of a DL. That requirement restricts the set of all possible DLs to
 
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