Biomedical Engineering Reference
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Fig. 5.4 (a1) Cross-sectional lattice image of synthesized CO 3 -HAp crystal with central planar
defect; (a2) higher magnification image of defect region. Central, one-unit-cell-thick OCP region
is labeled; white markings show expansion of apatite lattice across defect. (Reproduced with
permission from ref. [ 128 ]) (Copyright 1989, John Wiley and Sons) (b) Ap/OCP/Ap lamellar
mixed crystals grown on a cation-selective membrane in the presence of 1 ppm F. (Reproduced
with permission from ref. [ 135 ]) (Copyright 2001, S. Karger AG) (c1) Puffer enamel crystals in
early overgrowth stage. (Reproduced with permission from ref. [ 130 ]) (Copyright 1991, Springer)
(c2) Carp enameloid crystal in maturation stage. (Reproduced with permission from ref. [ 131 ])
(Copyright 1991, Springer) Horizontal bar corresponds to 10 nm. (d) Model of lateral epitaxial
overgrowth of enamel crystals: (A) epitaxial growth of apatite on OCP template with one-unit-
cell thickness; (B) lateral growth of isolated apatite units on template and fusion of neighboring
units; (C) thickening of apatite crystals by acquisition of apatite unit cells on their prism plane.
(Reproduced with permission from ref. [ 120 ]) (Copyright 1993, Springer)
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