Biomedical Engineering Reference
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Fig. 4.1 Analysis of retrograde flow in lamella region of migrating fish keratocyte (Adachi et al.
2009 ). ( a ) FSM image of fish keratocyte microinjected with quantum dots and imaged. ( b ) Filtered
image of the cell in ( a ). ( c ) Kymograph constructed using stripes taken from the region marked by
a line in ( b ). ( d ) Trajectories of two separate fluorescent speckles undergoing displacement due to
retrograde flow. The separation distance between the trajectories in x direction becomes shorter
toward the back of lamellipodia. CB stands for cell body, LE for leading edge and TE for trailing
edge (Adapted with permission from Elsevier Ltd.: [Journal of Biomechanics], copyright (2008))
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