Biomedical Engineering Reference
In-Depth Information
10. Gozuacik D, Kimchi A. (2006) DAPk protein family and
cancer. Autophagy 2, 74-79.
11. Michie AM, McCaig AM, Nakagawa R, Vukovic M. (2010)
Death-associated protein kinase (DAPK) and signal transduc-
tion: regulation in cancer. Febs. J. 277, 74-80.
12. Maller JL. (1993) On the importance of protein phosphoryl-
ation in cell cycle control. Mol. Cell Biochem. 128, 267-281.
13. Barik S. (1996) Protein phosphorylation and signal transduc-
tion. Subcell. Biochem. 26, 115-164.
14. Graves JD, Krebs EG. (1999) Protein phosphorylation and
signal transduction. Pharmacol. Ther. 82, 111-121.
15. Hanahan D, Weinberg RA. (2000) The hallmarks of cancer.
Cell 100, 57-70.
16. Cross TG, Scheel-Toellner D, Henriquez NV, Deacon E,
Salmon M, Lord JM. (2000) Serine/threonine protein kinases
and apoptosis. Exp. Cell. Res. 256, 34-41.
17. Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S.
(2002) The protein kinase complement of the human genome.
Science 298, 1912-1934.
18. Hanks SK, Quinn AM, Hunter T. (1988) The protein kinase
family: conserved features and deduced phylogeny of the
catalytic domains. Science 241, 42-52.
19. Hanks SK, Quinn AM. (1991) Protein kinase catalytic domain
sequence database: identification of conserved features of
primary structure and classification of family members. Meth-
ods Enzymol. 200, 38-62.
20. Deiss LP, Feinstein E, Berissi H, Cohen O, Kimchi A. (1995)
Identification of a novel serine/threonine kinase and a novel
15-kD protein as potential mediators of the gamma interferon-
induced cell death. Genes Dev. 9, 15-30.
21. Inbal B, Cohen O, Polak-Charcon S, Kopolovic J, Vadai E,
Eisenbach L, Kimchi A. (1997) DAP kinase links the control of
apoptosis to metastasis. Nature 390, 180-184.
22. Inbal B, Shani G, Cohen O, Kissil JL, Kimchi A. (2000) Death-
associated protein kinase-related protein 1, a novel serine/-
threonine kinase involved in apoptosis. Mol. Cell. Biol. 20,
1044-1054.
23. Cohen O, Feinstein E, Kimchi A. (1997) DAP-kinase is a
Ca2 รพ /calmodulin-dependent, cytoskeletal-associated protein
kinase, with cell death-inducing functions that depend on its
catalytic activity. Embo J. 16, 998-1008.
24. Bialik S, Kimchi A. (2006) The death-associated protein
kinases: structure, function, and beyond. Annu. Rev. Biochem.
75, 189-210.
25. Shani G, Henis-Korenblit S, Jona G, Gileadi O, Eisenstein M,
Ziv T, Admon A, Kimchi A. (2001) Autophosphorylation
restrains the apoptotic activity of DRP-1 kinase by
controlling dimerization and calmodulin binding. Embo J.
20, 1099-1113.
26. Gozuacik D, Kimchi A. (2004) Autophagy as a cell death and
tumor suppressor mechanism. Oncogene 23, 2891-2906.
27. Inbal B, Bialik S, Sabanay I, Shani G, Kimchi A. (2002) DAP
kinase and DRP-1 mediate membrane blebbing and the for-
mation of autophagic vesicles during programmed cell death.
J. Cell. Biol. 157, 455-468.
28. Shohat G, Spivak-Kroizman T, Cohen O, Bialik S, Shani G,
Berrisi H, Eisenstein M, Kimchi A. (2001) The pro-apoptotic
function of death-associated protein kinase is controlled by a
unique inhibitory autophosphorylation-based mechanism.
J. Biol. Chem. 276, 47460-47467.
29. Kawai T, Nomura F, Hoshino K, Copeland NG, Gilbert DJ,
Jenkins NA, Akira S. (1999) Death-associated protein kinase 2
is a new calcium/calmodulin-dependent protein kinase that
signals apoptosis through its catalytic activity. Oncogene 18,
3471-3480.
30. Bialik S, Berissi H, Kimchi A. (2008) A high throughput
proteomics screen identifies novel substrates of death-
associated protein kinase. Mol. Cell. Proteomics 7, 1089-1098.
31. Raveh T, Droguett G, Horwitz MS, DePinho RA, Kimchi A.
(2001) DAP kinase activates a p19ARF/p53-mediated
apoptotic checkpoint to suppress oncogenic transformation.
Nat. Cell. Biol. 3, 1-7.
32. Rizzi M, Tschan MP, Britschgi C, Britschgi A, Hugli B,
Grob TJ, et al. (2007) The death-associated protein kinase 2
is up-regulated during normal myeloid differentiation and
enhances neutrophil maturation in myeloid leukemic cells.
J. Leukoc. Biol. 81, 1599-1608.
33. Raveh T, Kimchi A. (2001) DAP kinase-a proapoptotic
gene that functions as a tumor suppressor. Exp. Cell. Res.
264, 185-192.
34. Katzenellenbogen RA, Baylin SB, Herman JG. (1999) Hyper-
methylation of the DAP-kinase CpG island is a common
alteration in B-cell malignancies. Blood 93, 4347-4353.
35. Raval A, Tanner SM, Byrd JC, Angerman EB, Perko JD, Chen
SS, et al. (2007) Downregulation of death-associated protein
kinase 1 (DAPK1) in chronic lymphocytic leukemia. Cell 129,
879-890.
36. Bai T, Tanaka T, Yukawa K, Maeda M, Umesaki N. (2004)
Reduced expression of death-associated protein kinase in
human uterine and ovarian carcinoma cells. Oncol. Rep. 11,
661-665.
37. Herman JG, Baylin SB. (2003) Gene silencing in cancer in
association with promoter hypermethylation. N. Engl. J. Med.
349, 2042-2054.
38. Kissil JL, Feinstein E, Cohen O, Jones PA, Tsai YC, Knowles
MA, et al. (1997) DAP-kinase loss of expression in various
carcinoma and B-cell lymphoma cell lines: possible implica-
tions for role as tumor suppressor gene. Oncogene 15, 403-
407.
39. Daskalakis M, Nguyen TT, Nguyen C, Guldberg P, Kohler G,
Wijermans P, et al. (2002) Demethylation of a hypermethylated
P15/INK4B gene in patients with myelodysplastic syndrome
by 5-Aza-2 0 -deoxycytidine (decitabine) treatment. Blood 100,
2957-2964.
40. Silverman LR, Mufti GJ. (2005) Methylation inhibitor therapy
in the treatment of myelodysplastic syndrome. Nat. Clin.
Pract. Oncol. 2 Suppl 1, S12-23.
41. Esteller M. (2005) DNA methylation and cancer therapy: new
developments and expectations. Curr. Opin. Oncol. 17, 55-60.
42. Hackanson B, Bennett KL, Brena RM, Jiang J, Claus R, Chen
SS, et al. (2008) Epigenetic modification of CCAAT/enhancer
Search WWH ::




Custom Search