Biomedical Engineering Reference
In-Depth Information
ribosome inactivating proteins non-covalently bound to
monoclonal antibody. Farmaco 51, 477-482.
23. Rathore D, Nayak SK, Batra JK. (1997) Overproduction of
fungal ribotoxin alpha-sarcin in Escherichia coli: generation
of an active immunotoxin. Gene 190, 31-35.
24. Better M, Bernhard SL, Lei SP, Fishwild DM, Carroll SF.
(1992) Activity of recombinant mitogillin and mitogillin
immunoconjugates. J. Biol. Chem. 267, 16712-16718.
25. Parente D, Raucci G, Celano B, Pacilli A, Zanoni L, Canevari
S, et al. (1996) Clavin, a type-1 ribosome-inactivating protein
from Aspergillus clavatus IFO 8605. cDNA isolation, heterol-
ogous expression, biochemical and biological characterization
of the recombinant protein. Eur. J. Biochem. 239, 272-280.
26. Goyal A, Batra JK. (2000) Inclusion of a furin-sensitive
spacer enhances the cytotoxicity of ribotoxin restrictocin
containing recombinant single-chain immunotoxins. Bio-
chem. J. 345(Pt 2), 247-254.
27. Martsev SP, Tsybovsky YI, Stremovskiy OA, Odintsov SG,
Balandin TG, Arosio P. (2004) Fusion of the antiferritin
antibody VL domain to barnase results in enhanced solubility
and altered pH stability. Protein Eng. Des. Sel. 17, 85-93.
28. Liu S, Bugge TH, Leppla SH. (2001) Targeting of tumor cells
by cell surface urokinase plasminogen activator-dependent
anthrax toxin. J. Biol. Chem. 276, 17976-17984.
29. Foster KA, Adams EJ, Durose L, Cruttwell CJ, Marks E,
Shone CC, et al. (2006) Re-engineering the target specificity
of Clostridial neurotoxins—a route to novel therapeutics.
Neurotox. Res. 9, 101-107.
30. Chovnick A, Schneider WP, Tso JY, Queen C, Chang CN.
(1991) A recombinant, membrane-acting immunotoxin. Can-
cer Res. 51, 465-467.
31. Gasanov SE, Rael ED, Gasanov NE, Vernon LP. (1995) In
vitro evaluation of Pyrularia thionin-anti-CD5 immunotoxin.
Cancer Immunol. Immunother. 41, 122-128.
32. Osusky M, Teschke L, Wang X, Wong K, Buckley JT. (2008)
A chimera of interleukin 2 and a binding variant of aerolysin
is selectively toxic to cells displaying the interleukin 2
receptor. J. Biol. Chem. 283, 1572-1579.
33. Cohen S, Cahan R, Ben-Dov E, Nisnevitch M, Zaritsky A,
Firer MA. (2007) Specific targeting to murine myeloma cells
of Cyt1Aa toxin from Bacillus thuringiensis subspecies isra-
elensis. J. Biol. Chem. 282, 28301-28308.
34. Choe S, Bennett MJ, Fujii G, Curmi PM, Kantardjieff KA,
Collier RJ. (1992) The crystal structure of diphtheria toxin.
Nature 357, 216-222.
35. Tsuneoka M, Nakayama K, Hatsuzawa K, Komada M,
Kitamura N, Mekada E. (1993) Evidence for involvement
of furin in cleavage and activation of diphtheria toxin. J. Biol.
Chem. 268, 26461-26465.
36. Gordon VM, Klimpel KR, Arora N, Henderson MA, Leppla
SH. (1995) Proteolytic activation of bacterial toxins by
eukaryotic cells is performed by furin and by additional
cellular proteases. Infect. Immun. 63, 82-87.
37. Neville DM, Scharff J, Srinivasachar K. (1993) Anti-T cell
immunotoxins: a look at post-endocytotic receptor-mediated
routing. J. Control. Release 24, 133-144.
38. London E. (1992) Diphtheria toxin: membrane interaction and
membrane translocation. Biochim. Biophys. Acta 1113, 25-51.
39. Donovan JJ, Simon MI, Draper RK, Montal M. (1981)
Diphtheria toxin forms transmembrane channels in planar
lipid bilayers. Proc. Natl. Acad. Sci. USA 78, 172-176.
40. Kagan BL, Finkelstein A, Colombini M. (1981) Diphtheria
toxin fragment forms large pores in phospholipid bilayer
membranes. Proc. Natl. Acad. Sci. USA 78, 4950-4954.
41. Wiedlocha A, Madshus IH, Mach H, Middaugh CR, Olsnes S.
(1992) Tight folding of acidic fibroblast growth factor pre-
vents its translocation to the cytosol with diphtheria toxin as
vector. Embo J. 11, 4835-4842.
42. Falnes PO, Choe S, Madshus IH, Wilson BA, Olsnes S.
(1994) Inhibition of membrane translocation of diphtheria
toxin A-fragment by internal disulfide bridges. J. Biol. Chem.
269, 8402-8407.
43. Ren J, Kachel K, Kim H, Malenbaum SE, Collier RJ, London
E. (1999) Interaction of diphtheria toxin T domain with
molten globule-like proteins and its implications for trans-
location. Science 284, 955-957.
44. Ratts R, Zeng H, Berg EA, Blue C, McComb ME, Costello
CE, et al. (2003) The cytosolic entry of diphtheria toxin
catalytic domain requires a host cell cytosolic translocation
factor complex. J. Cell Biol. 160, 1139-1150.
45. Van Ness BG, Howard JB, Bodley JW. (1980) ADP-
ribosylation of elongation factor 2 by diphtheria toxin. Isola-
tion and properties of the novel ribosyl-amino acid and its
hydrolysis products. J. Biol. Chem. 255, 10717-10720.
46. Yamaizumi M, Mekada E, Uchida T, Okada Y. (1978) One
molecule of diphtheria toxin fragment A introduced into a cell
can kill the cell. Cell 15, 245-250.
47. Allured VS, Collier RJ, Carroll SF, McKay DB. (1986)
Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-
Angstrom resolution. Proc. Natl. Acad. Sci. USA 83, 1320-
1324.
48. Kounnas MZ, Morris RE, Thompson MR, FitzGerald DJ,
Strickland DK, Saelinger CB. (1992) The alpha
2-macroglobulin receptor/low density lipoprotein receptor-
related protein binds and internalizes Pseudomonas exotoxin
A. J. Biol. Chem. 267, 12420-12423.
49. Pastrana DV, Hanson AJ, Knisely J, Bu G, Fitzgerald DJ.
(2005) LRP 1 B functions as a receptor for Pseudomonas
exotoxin. Biochim. Biophys. Acta 1741, 234-239.
50. Debinski W, Pastan I. (1994) An immunotoxin with increased
activity and homogeneity produced by reducing the number
of lysine residues in recombinant Pseudomonas exotoxin.
Bioconjug. Chem. 5, 40-46.
51. Onda M, Beers R, Xiang L, Nagata S, Wang QC, Pastan I.
(2008) An immunotoxin with greatly reduced immunogenic-
ity by identification and removal of B cell epitopes. Proc.
Natl. Acad. Sci. USA 105, 11311-11316.
52. Weldon JE, Xiang L, Chertov O, Margulies I, Kreitman RJ,
FitzGerald DJ, et al. (2009) A protease-resistant immuno-
toxin against CD22 with greatly increased activity against
CLL and diminished animal toxicity. Blood 113, 3792-
3800.
Search WWH ::
Custom Search