Biomedical Engineering Reference
In-Depth Information
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5
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Sample
FIGURE 19.48
Microhardness of the TiO
2
fi lms. (From Leng, Y.X. et al.,
Surf. Coating Tech
., 156, 295,
2002. With permission.)
(a)
(b)
FIGURE 19.49
SEM (1000
×
) images showing less platelet adhesion on TiO
2
(a) than LTIC (b). (From Chu,
P.K. et al.,
Mater. Sci. Eng
.
R
Rep.
,
36, 143, 2002. With permission.)
surface. It is postulated that the denaturing of fi brinogen is related to the charges of fi brinogen
transferred to the material, as shown in Figure 19.50. During this process, fi brinogen decomposes
and transforms into fi brin monomer and fi brin peptides, followed by cross-linking to form the irre-
versible thrombus [170].
