Biomedical Engineering Reference
In-Depth Information
191. Hirsh, J. et al., Low molecular weight heparins (LMWH) in the treatment of patients with acute venous
thromboembolism,
Thromb. Haemost
., 74, 360, 1995.
192. GUSTO IIb investigators, A comparison of recombinant hirudin with heparin for the treatment of acute
coronary syndromes. The global use of strategies to open occluded coronary arteries (GUSTO) IIb
investigators,
N. Engl. J. Med
., 335, 775, 1996.
193. Sarembock, I. et al., Effectiveness of hirulog in reducing restenosis after balloon angioplasty of athero-
sclerotic femoral arteries in rabbits,
J. Vasc. Res
., 33, 308, 1996.
194. Verstraete, M., New developments in antiplatelet and antithrombotic therapy,
Eur. Heart J
.,
16, 16, 1995.
195. Corea, F. et al., Secondary prevention of cardioembolic stroke: Oldest and newest promises,
Clin. Exp.
Hypertens
., 28, 413, 2006.
196. Marki, W.E., The anticoagulant and antithrombotic properties of hirudins,
Thromb. Haemost
.,
64, 344, 1991.
197. Egner, U., Hoyer, G.A., and Schleuning, W.D., Rational design of hirulog-type inhibitors of thrombin,
J. Comput. Aided Mol. Des
., 8, 479, 1994.
198. Agnelli, G. et al., Sustained antithrombotic activity of hirudin after its plasma clearance: Comparison
with heparin,
Blood
, 80, 960, 1992.
199. Cardot, J.M., Lefevre, G.Y., and Godbillon, J.A., Pharmacokinetics of rec-hirudin in healthy volunteers
after intravenous administration,
J. Pharmacokinet. Biopharm
., 22, 147, 1994.
200. Fox, I. et al., Anticoagulant activity of Hirulog, a direct thrombin inhibitor, in humans,
Thromb.
Haemost
., 69, 157, 1993.
201. Zoldhelyi, P. et al., Persistent thrombin generation in humans during specifi c thrombin inhibition with
hirudin,
Circulation
, 90, 2671, 1994.
202. Schumacher, W.A. et al., Effects of antithrombotic drugs in a rat model of aspirin-insensitive arterial
thrombosis,
Thromb. Haemost
., 69, 509, 1993.
203. Scott, N.A. et al., Local delivery of an antithrombin inhibits platelet-dependent thrombosis,
Circulation
,
90, 1951, 1994.
204. Hollenbach, S. et al., A comparative study of prothrombinase and thrombin inhibitors in a novel rabbit
model of non-occlusive deep vein thrombosis,
Thromb. Haemost
., 71, 357, 1994.
205. Schwienhorst, A., Direct thrombin inhibitors—a survey of recent developments,
Cell Mol. Life Sci
., 63,
2773, 2006.
206. Paredes, N. et al., Mechanisms responsible for catalysis of the inhibition of factor Xa or thrombin by
antithrombin using a covalent antithrombin-heparin complex,
J. Biol. Chem
., 278, 23398, 2003.
207. Hatton, M.W.C. et al., Tritiation of commercial heparins by reaction of NaB3H4: Chemical analysis and
biological properties of the product,
Anal. Biochem
., 106, 417, 1980.
208. Pletcher, C.H. and Nelsestuen, G.L., The rate-determining step of the heparin-catalyzed antithrombin/
thrombin reaction is independent of thrombin,
J. Biol. Chem
., 257, 5342, 1982.
209. Muir, J.M. et al., A histomorphometric comparison of the effects of heparin and low molecular weight
heparin on cancellous bone in rats,
Blood
, 89, 3236, 1997.
210. Amiral, J. et al., Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-
induced thrombocytopenia,
Thromb. Haemost
., 68, 95, 1992.
211. Lane, D.A. et al., Anticoagulant activities of heparin oligosaccharides and their neutralization by plate-
let factor 4,
Biochem. J
., 218, 725, 1984.
212. Sprung, C.L. et al., Distribution of proteins in pulmonary edema,
Am. Rev. Respir. Dis
., 136,
957, 1987.
213. Holter, J. et al., Protein permeability in the adult respiratory distress syndrome. Loss of size selectivity
of the alveolar epithelium,
J. Clin. Invest
., 78, 1513, 1986.
214. Brus, F. et al., Leakage of protein into lungs of preterm ventilated rabbits is correlated with
activation of clotting, complement, and polymorphonuclear leukocytes in plasma,
Pediatr. Res
.,
39, 958, 1996.
215. Bachofen, M. and Weibel, E.R., Structural alterations of lung parenchyma in the adult respiratory dis-
tress syndrome,
Clin. Chest Med
., 3, 35, 1982.
216. Gitlin, D. and Craig, J., The nature of the hyaline membrane in asphyxia of the newborn,
Pediatrics
,
17, 64, 1956.
217. Jobe, A.H., Pulmonary surfactant therapy,
N. Engl. J. Med
., 328, 861, 1993.
218. Long, W., Thompson, T., and Sundell, H., Effects of two rescue doses of a synthetic surfactant on mor-
tality rate and survival without bronchopulmonary dysplasia,
J. Pediatr
., 118, 595, 1991.
