Biomedical Engineering Reference
In-Depth Information
TABLE 14.9
Examples of Immunobiosensors Prepared by Antigens (Antibodies)
Target Substances
Substrates
Signal Transducers
Immobilization Method of Antigen (Antibody)
Type
Ref.
Atrazine antibodies
Atrazine
Au electrode of 10 MHz
piezoelectric crystals
Atrazine antibodies were layered onto the gold electrode
precoated with protein A
Piezoelectric crystal
immunobiosensor
140
Protamine
Immunoglobulin M
(IgM)
Piezoelectric crystal device
Protamine was immobilized by using either
γ-aminopropyltriethoxy silane (γ-APTES) or 2.2.2-
tril uoroethanesulfonyl chloride (tresyl chloride)
Piezoelectric crystal
immunobiosensor
141
A-fetoprotein (AFP) antibody
AFP
MHz AT-cut quartz crystals
with Au electrode
AFP antibody was immobilized onto the amine-coated
surface by glutaraldehyde (GA) cross-linking
Piezoelectric crystal
immunobiosensor
142
Antiestrogen antibody
Estrone
Pt electrode
Antibody was modii ed on the electrode by the direct
electrochemical polymerization of pyrrole
Electrochemical
immunobiosensor
143
Helicobacter pylori
antigens
Immunoglobulin G
(IgG) antibodies
GCE
H. pylori
antigens were immobilized on the
3-aminopropyl-modii ed controlled pore glass
Electrochemical
immunobiosensor
144
Carcinoembryonic antibody
Carcinoembryonic
antigen
Screen-printed carbon
electrode
Carcinoembryonic antigen was immobilized on the
electrode with colloid Au and chitosan membrane
Electrochemical
immunobiosensor
145
Sulfadiazine (SDZ)
SDZ antibody and SDZ
residues sample
Dextran-coated silicon chip
SDZ was immobilized onto the surface of the dextran-
coated silicon chip
Optical
immunobiosensor
146
Antichloramphenicol (CAP)
antibody
CAP
Solid support devised by
installing a l ow-through cell
Anti-CAP antibody was immobilized onto Biodyne B
membrane pieces by a dipping procedure
Chemiluminescent
immunobiosensor
147
Anti-2,4-
dichlorophenoxyacetic acid
(2,4-D) polyclonal antibodies
2,4-D
Chemiluminescent l ow
injection
Anti-2,4-D polyclonal antibodies are directly labeled
with horseradish peroxidase
Chemiluminescent
immunobiosensor
148
Protein A
Anti-BSA
Surface plasmon resonance
Protein A was immobilized on the Au surface by the
heterobifunctional linker of
N
-succinimidyl-3-(2-
pyridyldithio)propionate (SPDP)
Surface plasmon
resonance
immunobiosensor
149
Ivermectin-oxime
Ivermectin in bovine
liver
Surface plasmon resonance
Ivermectin-oxime was immobilized onto the surface of
a sensor chip by an amidating reaction by NHS/EDC
Surface plasmon
resonance
immunobiosensor
150
