Biomedical Engineering Reference
In-Depth Information
TABLE 14.4
Examples of Biosensors Prepared by COD or CEH/COD
Enzymes
Substrates
Signal Transducers
Immobilization Method of Enzyme
Type
Ref.
COD
Cholesterol
GCE
COD was immobilized in a layer of silicic sol-gel
matrix on the top of Prussian Blue
Amperometric
34
COD
Cholesterol
Pt electrode
COD was entrapped within a composite poly-
(2-hydroxyethyl methacrylate) (p(HEMA))/
polypyrrole (p(pyrrole)) membrane
Amperometric
35
COD
Cholesterol
Au electrode
COD was cross-linked with octadecanethiol (ODT)
self-assembled (SA) monolayer by nitrene reaction
of 1-l uoro-2-nitro-4-azidobenzene (FNAB)
Surface plasmon
resonance
(SPR)
36
COD
Cholesterol
Pt electrode
COD was immobilized on the electrode by a layer-
by-layer (LBL) technique with poly(ethylene imine)
(PEI)
Amperometric
37
COD
Cholesterol
Ru(phen)
2
+
l uorescent
membrane
COD was immobilized in the carrier of cellulose
acetate
Optical
38
COD
Cholesterol
Fluorescent dye
COD was immobilized covalently on a nylon
membrane
Optical
39
CEH/COD
Cholesterol ester
Pt electrode
CEH and COD were immobilized on the porous
composite material prepared from acetylene black
and Tel on emulsion by adsorption
Amperometric
40
CEH/COD
Total cholesterol
in serum
Bifurcated i ber-optic
bundle
CEH and COD were coimmobilized on a preactivated
nylon membrane
Optical
41
CEH/COD
Cholesterol
oleate
ITO-coated glass plates
CEH and COD were immobilized on
electrochemically prepared polyaniline (PANI) i lms
using covalent linkage with glutaraldehyde
Amperometric
42
CEH/COD
Total cholesterol
in serum
Hydrogen peroxide
electrode
CEH and COD were immobilized on octyl-agarose
gel, activated with cyanogen bromide and placed in
a reactor
Amperometric
43
