Biomedical Engineering Reference
In-Depth Information
TABLE 1.7
Biocomposites Designed for Bone Tissue Engineering
Biocomposites
Compressive (C),
Tensile(T), Flexural
Strength (F) (MPa)
Percentage of
Ceramic (%)
Pore Size
(
µ
m)
Ultimate
Strain (%)
Toughness
(kJ/m
2)
Porosity (%)
Modulus (MPa)
References
Ceramic
Polymer
Dense composites
HA i ber
1.75-2.47
×
10
3
PDLLA
2-10.5 (vol.)
Not applicable
45 (F)
133
6.4-12.8
×
10
3
PLLA
10-70 (wt.)
50-60 (F)
0.7-2.3
134
1.1
×
10
3
HA
PLGA
40-85 (vol.)
22 (F)
5.29
135,136
2.15
×
10
3
2.6
×
10
3
Chitosan
Chitosan
+
PLGA
40-85 (vol.)
40-85 (vol.)
12 (F)
43 (F)
0.092
9.77
136
136
PPhos
85-95 (wt.)
137
Collagen
50-72 (wt.)
138
5.18
×
10
3
191-134
β-TCP
PLLA-
co
-PEH
PPF
75 (wt.)
25 (wt.)
51 (F)
7.5-7.7 (C)
132
139
0.9-5.7
×
10
3
A/W
PE
10-50 (vol.)
18-28 (F)
140
3.5-6
×
10
3
Ca
3
(CO
3
)
2
PLLA
30 (wt.)
50 (C)
141
12-18
×
10
3
Human cortical bone
50-150 (T)
130-180 (C)
28,43-46
Porous composites
Amorphous CaP
>
100
PLGA
28-75 (wt.)
75
65
142,143
β-TCP
Chitosan-Gelatin
10-70 (wt.)
322-355
0.32-0.88 (C)
3.94-10.88
144
100
×
300
HA
PLLA
50 (wt.)
85-96
0.39 (C)
10-14
145
PLGA
60-75 (wt.)
81-91
800-1800
0.07-0.22 (C)
2-7.5
146
PLGA
30-40
110-150
337-1459
147
Bioglass
PLGA
75 (wt.)
43
89
0.42 (C)
51
64,148,149
∼
100
∼
10
PLLA
20-50 (wt.)
77-80
1.5-3.9 (T)
137-260
1.1-13.7
150
PLGA
0.1-1 (wt.)
50-300
151
∼
100
10-50
PDLLA
5-29 (wt.)
94
0.07-0.08 (C)
0.65-1.2
7.21-13.3
111,112,152
