Biomedical Engineering Reference
In-Depth Information
TABLE 1.6
Physical Properties of Synthetic, Biocompatible, and Biodegradable Polymers Investigated as Scaffold Materials
Tensile or
Compressive*
Strength (MPa)
Melting Point,
T
m
(°C)
Glass Transition
Point,
T
g
(°C)
Degradation
Time (months)
Ultimate
Elongation (%)
Polymers
Modulus (GPa)
References
Bulk degradable polymers
PDLLA
Amorphous
55-60
12-16
Pellet: 35-150
*
Film or disk: 29-35
Film or disk:
1.9-2.4
Pellet: 0.5-8.0
Film or disk:
5.0-6.0
90,94,95
PLLA
173-178
60-65
>
24
Pellet: 40-120
Film or disk: 28-50
Fiber: 870-2300
Film or disk:
1.2-3.0
Fiber: 10-16
Pellet: 2.0-10.0
Film or disk:
2.0-6.0
Fiber: 12-26
90,94
PGA
225-230
35-40
6-12
Fiber: 340-920
Fiber: 7-14
Fiber: 15-25
90,96,97
PLGA
Amorphous
45-55
Adjustable
41.4-55.2
1.4-2.8
3-10
28
PPF
Bulk
2-30*
28,30
PCL
58
−
72
Bulk
700
98
Surface erosive polymers
Poly(anhydrides)
150-200
Surface
25-27
30-40*
0.14-1.4
28,30,99
Poly(ortho-esters)
30-100
Surface
4-16*
2.5-4.4
28,100
Polyphosphazene
−
66-50
242
Surface
101,102
Type I collagen
Bulk
Uncross-linked i ber:
0.91-7.2
Cross-linked i ber:
46.8-68.8
Uncross-linked
i ber: 1.8-46
×
10
-
3
Cross-linked i ber:
0.383-0.766
Uncross-linked
i ber: 24.1-68.0
Cross-linked i ber:
11.6-15.6
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