Biology Reference
In-Depth Information
Table 2.9 Characterization of the active site structure and fluctuations for the C3 and G8
mutants in activated precursor states
d-C3U/
G8A
d-C3U/
G8D
d-C3G/
G8C
d-WT
d-U7C
d-C3U d-G8A
d-G8I
d-G8D
r
Nu
3.59
(0.17)
3.64
(0.17)
3.65
(0.16)
3.73
(0.2)
3.6
(0.16)
3.69
(0.23)
3.64
(0.21)
3.34
(0.13)
3.61
(0.17)
y
inl
156.8
(7.9)
153.6
(8.7)
154.9
(7.5)
148.1
(8.9)
155.7
(7.6)
149
(12.7)
152.5
(10.4)
164.1
(7.4)
155.4
(8.2)
F
0.49
(0.09)
0.46
(0.09)
0.46
(0.08)
0.41
(0.1)
0.48
(0.08)
0.43
(0.12)
0.46
(0.11)
0.65
(0.1)
0.48
(0.09)
d
0
2.94
(0.13)
2.93
(0.12)
2.93
(0.13)
2.95
(0.12)
2.93
(0.12)
2.93
(0.13)
3
(0.13)
2.97
(0.13)
2.95
(0.13)
r
HB
2.03
(0.37)
1.94
(0.14)
1.93
(0.14)
1.93
(0.2)
1.95
(0.14)
1.95
(0.18)
1.91
(0.13)
1.86
(0.1)
1.96
(0.15)
y
HB
154.6
(11.9)
155.8
(9.4)
155.6
(9.4)
158.4
(9.2)
155.5
(9.3)
157.2
(9.8)
158.1
(9.3)
161.2
(8.4)
156
(9.2)
%
95
100
100
99
100
100
100
100
100
%72
73
73
82
74
77
81
91
75
r
HA
2.61
(0.77)
2.5
(0.79)
2.63
(0.76)
4.13
(0.63)
2.6
(0.9)
2.44
(0.52)
2.46
(0.44)
3.53
(0.74)
2.42
(0.57)
y
HA
131.8
(34.5)
135.5
(35.2)
122.3
(34.3)
82.6
(21.4)
130.5
(38)
137.3
(27.7)
139.6
(24.6)
117.2
(31.2)
138
(29.3)
%9 5 7
1
69
74
81
20
77
%5 4 4
0
41
37
34
1
41
r
NN
2.96
(0.1)
2.96
(0.09)
3.78
(0.21)
6.68
(0.42)
3.04
(0.15)
2.92
(0.11)
3.57
(0.19)
3.03
(0.12)
2.97
(0.09)
r
1
1.92
(0.15)
2.02
(0.17)
-
-
-
-
1.98
(0.11)
2.23
(0.28)
1.9
(0.13)
y
1
160.9
(10)
163.8
(8.5)
-
-
-
-
163.1
(9.1)
157.9
(13.1)
163.7
(8.3)
r
2
1.98
(0.1)
1.99
(0.1)
1.91
(0.15)
-
2.08
(0.17)
1.94
(0.11)
2.06
(0.16)
2.06
(0.14)
2.01
(0.1)
y
2
163.2
(8.3)
162.3
(8.8)
160.6
(10.7)
-
160.8
(10.1)
163.9
(8.3)
160.7
(10.8)
163.1
(9.8)
160.1
(8.6)
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