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0.6
2796.2
0.0
100.0
(a)
(b)
1.6×10
6
1.2×10
6
8.0×10
5
4.0×10
5
R
=0.89
R
< 0.0001
0.0
0
200 400
Integrated O.D. via fluorescence imaging
600
(c)
0.6
0.4
0.2
0
20
30
40
50
Age (years)
60
70
80
90
(d)
FIGURE 6.10
RRI images of MP distributions obtained for the same subject with (a) RRI and (b) lipofucsin
l uorescence-based imaging. (c) Comparison of integrated MP densities obtained for 17 subjects with both
imaging methods. Vertical scale shows integrated MP densities derived from RRI images by integrating inten-
sities over the whole macular region; horizontal scale shows corresponding densities derived via l uorescence
imaging. A high correlation coefi cient of
R
= 0.89 is obtained for both methods. (d) Age dependence of MP
levels, measured with a lipofucsin l uorescence-based method (
R
= −0.47,
p
< 0.0001). (From Sharifzadeh, M.
et al.,
J. Opt. Soc. Am. A
, 25, 947, 2008. With permission; Sharifzadeh, M. et al.,
J. Opt. Soc. Am. A
, 23, 2373,
2006. With permission.)
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