Biomedical Engineering Reference
In-Depth Information
DNA X-linked polymer
Gel preparation
Chemical structure
Notes
pHEMA,
Crosslink: L2 (replacing EGDMA)
Pore size:
10 µm to 20 µm
poly-(hydroxyethyl methacrylate)
(Bakshi et al. 2004, Carone &
Hasenwinkel 2006, Flynn et al. 2003)
HEMA (Aldrich, St. Louis, MO)
(20%-60%)
Initiator-catalyst (APS-TEMED)
pHPMA,
Crosslink: L2 (replacing DMHA)
Pore size:
10 µm to 50 µm
poly-(hydroxypropyl-
methacrylamide) (Duconseille et al.
1998, St'astny et al. 2002)
HPMA monomer
Initiator (AIBN)
Table 3. DNA crosslinked vinyl polymers such as pHEMA and pHPMA.
8. Abbreviation
dsDNA: double-stranded DNA; ssDNA: single-stranded DNA; ECM: extracellular matrix;
bp: basepair; nt: nucleotide.
9. Reference
Aldaye FA, Palmer AL, Sleiman HF. 2008. Assembling materials with DNA as the guide.
Science
321: 1795-9
Alemdaroglu FE, Alemdaroglu NC, Langguth P, Herrmann A. 2008. DNA Block Copolymer
Micelles - A Combinatorial Tool for Cancer Nanotechnology.
Advanced Materials
20:
899-902
Alemdaroglu FE, Herrmann A. 2007. DNA meets synthetic polymers--highly versatile
hybrid materials.
Org Biomol Chem
5: 1311-20
Amiya T, Tanaka T. 1987. Phase Transitions in Cross-Linked Gels of Natural Polymers.
Macromolecules
20: 1162-64
Bakshi A, Fisher O, Dagci T, Himes BT, Fischer I, Lowman A. 2004. Mechanically engineered
hydrogel scaffolds for axonal growth and angiogenesis after transplantation in
spinal cord injury.
J Neurosurg Spine
1: 322-9
Ball P. 2005. Synthetic biology for nanotechnology.
Nanotechnology
16: R1-R8
Bart Haegeman DV, Jean-Jacques Godon and Jérôme Hamelin. 2008. DNA reassociation
kinetics and diversity indices: richness is not rich enough.
Oikos
Berashevich J, Chakraborty T. 2008. How the surrounding water changes the electronic and
magnetic properties of DNA.
J Phys Chem B
112: 14083-9
Biggins JB, Prudent JR, Marshall DJ, Thorson JS. 2006. A continuous assay for DNA cleavage
using molecular break lights.
Methods Mol Biol
335: 83-92
