Biomedical Engineering Reference
In-Depth Information
5. Conclusion
Rat mesenchymal stem cells are able to differentiate when they are cultivated in
chondrogenic medium. These cells can colonize scaffolds and differentiate inside them.
Therefore, when these constructs were subcutaneously grafted in the rat dorsal region we
verified that cells maintained a differentiated phonotype after 6 weeks. All together, we
concluded that chitosan and gelatin are good candidates for scaffolds used to differentiate
stem cells with chondrogenic treatment.
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