Biology Reference
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Figure 1.10 Map sequence illustrating the different exclusion layers applied by
region. Maps are shown by region: Asia (A), Asia-Pacific (B), the Americas (C) and Africa+.
Panel 1  =  all regions of the regional P. vivax endemic countries; 2  =  downgrading or
exclusion of risk informed by annual parasite incidence data ( Pv API); 3  =  additional
exclusion of risk informed by the biological temperature mask; 4  =  additional down-
grading or exclusion of risk informed by the aridity mask; 5  =  additional downgrad-
ing or exclusion of risk informed by medical intelligence and international travel and
health guidelines; 6  =  the final limits definition after additionally downgrading risk in
stable areas predicted to have very low prevalence by the model-based geostatistics
(MBG) model. Stable transmission is shown in red, unstable transmission in pink, P. vivax
malaria free areas in grey and countries non-endemic for P. vivax or outside of the region
in white. For interpretation of the references to colour in this figure legend, the reader is
referred to the online version of this topic.
Pv API data, which report the number of confirmed P. vivax malaria cases
per administrative unit per 1000 people per annum (p.a.) from Pv MECs,
were used to further constrain the spatial limits of infection ( Fig. 1.10 A2-
D2). Pv API data were obtained from a variety of sources which are provided
in detail elsewhere ( Gething et al., 2012 ). Data were unavailable for 41 of
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