Biology Reference
In-Depth Information
Figure 4.1
The chemotherapeutic compartments in vivax malaria. (
Created by Prof.
Wallace Peters with art by Ms. Andrea Darlow, reprinted with their consent and the per-
mission of the publishers of Clinical Microbiology Review where it was originally published
(
Baird, 2009
)). For colour version of this figure, the reader is referred to the online version
of this topic.
prophylaxis' in connection with ending travel without a primary attack)
is used specifically for this application (
Hill et al., 2006
). We recommend
'PART' for radical cure of ill patients and 'post-travel PART' for healthy
travellers.
Causal prophylaxis
involves drugs active against early develop-
mental forms in hepatocytes, thus preventing both the acute attack and
the seeding of the liver with hypnozoites negating the need for post-travel
PART. Daily primaquine during exposure achieves this and is termed
'primaquine primary prophylaxis'.
