Biology Reference
In-Depth Information
organogenesis
( Akasaka et al., 2001 ).
WOX5 ( Bratzel,
L´pez-Torrej´n,
Koch, Del Pozo, &
Calonje, 2010 ).
Cbx8/Pc3,
Cbx7, Cbx6,
Cbx4/Pc2,
Cbx2/M33
Embryo: From the five
homologues, only
Cbx2 has been
functionally studied
and loss of function
results in perinatal
lethality, as well as
male-to-female sex
reversal, meiotic
defects and
chromosome
instability ( Baumann &
De La Fuente, 2011;
Katoh-Fukui et al.,
1998 ).
Pc
Pc loss of function is
embryonic lethal and
giving a strong
homeotic phenotype,
which is enhanced by
overexpression of BX-
C . Derepression of
Hox genes in Pc
mutants ( Lewis, 1978 ).
LHP1/
TLF2
A homologue of fly
and mouse HP1 , but
localizing to
euchromatin and
interacting with the
other PRC1 members
in plants. Mutant lhp1
plants show pleiotropic
phenotypes with
overall size reduction,
changes in leaf
morphology, early
flowering. LHP1 is also
required for the
repression of FLC in
the process of
vernalization ( Gaudin
et al., 2001 ; Sung
et al., 2006 ).
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