Skeletal Mechanoresponsiveness: Effects of Sex Hormones - Skeletal Aging and Osteoporosis: Biomechanics and Mechanobiology - page 230

70. Dupont, S., Krust, A., Gansmuller, A., Dierich, A., Chambon, P., Mark, M.: Effect of single
and compound knockouts of estrogen receptors a (ERa) and b (ERb) on mouse reproductive
phenotypes. Development 127(19), 4277-4291 (2000)
71. Feng, Y., Manka, D., Wagner, K.U., Khan, S.A.: Estrogen receptor-a expression in the
mammary epithelium is required for ductal and alveolar morphogenesis in mice. Proc. Natl.
Acad. Sci. U S A 104(37), 14718-14723 (2007). doi: 10.1073/pnas.0706933104
72. Lubahn, D.B., Moyer, J.S., Golding, T.S., Couse, J.F., Korach, K.S., Smithies, O.: Alteration
of reproductive function but not prenatal sexual development after insertional disruption of
the mouse estrogen receptor gene. Proc. Natl. Acad. Sci. U S A 90(23), 11162-11166 (1993)
73. Lindberg, M.K., Alatalo, S.L., Halleen, J.M., Mohan, S., Gustafsson, J.A., Ohlsson, C.:
Estrogen receptor specificity in the regulation of the skeleton in female mice. J. Endocrinol.
171(2), 229-236 (2001). JOE04348 [pii]
74. Vidal, O., Lindberg, M., Savendahl, L., Lubahn, D.B., Ritzen, E.M., Gustafsson, J.A., Ohlsson, C.:
Disproportional body growth in female estrogen receptor-alpha-inactivated mice. Biochem.
Biophys. Res. Commun. 265(2), 569-571 (1999). doi: 10.1006/bbrc.1999.1711
75. Parikka, V., Peng, Z., Hentunen, T., Risteli, J., Elo, T., Vaananen, H.K., Harkonen, P.:
Estrogen responsiveness of bone formation in vitro and altered bone phenotype in aged
estrogen receptor-alpha-deficient male and female mice. Eur. J. Endocrinol. 152(2), 301-314
(2005). doi: 10.1530/eje.1.01832
76. Vidal, O., Lindberg, M.K., Hollberg, K., Baylink, D.J., Andersson, G., Lubahn, D.B., Mohan, S.,
Gustafsson, J.A., Ohlsson, C.: Estrogen receptor specificity in the regulation of skeletal growth
and maturation in male mice. Proc. Natl. Acad. Sci. U S A 97(10), 5474-5479 (2000). 97/10/5474
[pii]
77. De Souza, R.L., Matsuura, M., Eckstein, F., Rawlinson, S.C., Lanyon, L.E., Pitsillides, A.A.:
Non-invasive axial loading of mouse tibiae increases cortical bone formation and modifies
trabecular organization: A new model to study cortical and cancellous compartments in a
single loaded element. Bone 37(6), 810-818 (2005). doi: 10.1016/j.bone.2005.07.022
78. Gross, T.S., Srinivasan, S., Liu, C.C., Clemens, T.L., Bain, S.D.: Noninvasive loading of the
murine tibia: An in vivo model for the study of mechanotransduction. J. Bone Miner. Res.
17(3), 493-501 (2002). doi: 10.1359/jbmr.2002.17.3.493
79. Lee, K.C., Maxwell, A., Lanyon, L.E.: Validation of a technique for studying functional
adaptation of the mouse ulna in response to mechanical loading. Bone 31(3), 407-412 (2002).
doi: S8756328202008426
80. Zaman, G., Saxon, L.K., Sunters, A., Hilton, H., Underhill, P., Williams, D., Price, J.S.,
Lanyon, L.E.: Loading-related regulation of gene expression in bone in the contexts of
estrogen deficiency, lack of estrogen receptor alpha and disuse. Bone 46(3), 628-642 (2010).
S8756-3282(09)01989-9 [pii]
81. Krege, J.H., Hodgin, J.B., Couse, J.F., Enmark, E., Warner, M., Mahler, J.F., Sar, M., Korach, K.S.,
Gustafsson, J.A., Smithies, O.: Generation and reproductive phenotypes of mice lacking estrogen
receptor beta. Proc. Natl. Acad. Sci. U S A 95(26), 15677-15682 (1998)
82. Saxon, L.K., Robling, A.G., Castillo, A.B., Mohan, S., Turner, C.H.: The skeletal
responsiveness to mechanical loading is enhanced in mice with a null mutation in estrogen
receptor-beta. Am. J. Physiol. Endocrinol. Metab. 293(2), 484-491 (2007). doi: 10.1152/
ajpendo.00189.2007
83. Windahl, S.H., Vidal, O., Andersson, G., Gustafsson, J.A., Ohlsson, C.: Increased cortical
bone mineral content but unchanged trabecular bone mineral density in female ERb(-/-)
mice. J Clin Invest 104(7), 895-901 (1999). doi: 10.1172/JCI6730
84. Onoe, Y., Miyaura, C., Ohta, H., Nozawa, S., Suda, T.: Expression of estrogen receptor beta
in rat bone. Endocrinology 138(10), 4509-4512 (1997)
85. Chagin, A.S., Lindberg, M.K., Andersson, N., Moverare, S., Gustafsson, J.A., Savendahl, L.,
Ohlsson, C.: Estrogen receptor-b inhibits skeletal growth and has the capacity to mediate
growth plate fusion in female mice. J. Bone Miner. Res. 19(1), 72-77 (2004). doi: 10.1359/
JBMR.0301203