Biomedical Engineering Reference
In-Depth Information
Table 3
(continued)
% Change per decade*
Authors
Materials
Method
Study design
Bone
Sex
TA
MA
CA
Tot.vBMD
Trab.vBMD
Sigurdsson et al. [ 8 ]
1715 subjects
(908 female,
807 male)
67-93 years
QCT
CS
Femoral Neck
Female
1.8
-
-6.3
-8.5
-22.6
Male
2.1
-
-1.7
-2.6
-14.2
TA, total (subperiosteal) area; MA, medullary area (called trabecular area in some papers); CA, cortical bone area; Tot.vBMD, avg. bone mineral density of
total volume; Trab.vBMD, average bone mineral density of trabecular volume
All results based on cross-sectional (CS) study design
*Percent change calculated using slope of regression line (e.g, TA vs. age), multiplied by 10 and divided by overall mean (unless noted otherwise)
Slopes are taken from papers (if reported), or determined by linear regression from data presented in papers
(NS) regression is not statistically significant, p [ 0.05
Distal Tibia: 4 % site; location given as percent of limb length, relative to the distal end; Femoral Neck: mid-portion of neck
a
regressions based on mean values for the age groups reported
b
from Table 2 of paper, recalculated based on estd. overall means
c
from Table 4 of paper, recalculated based on estd. overall means
d
Yuen reports slopes for \60 and [60 years in Table 4 of paper; values shown here are computed from slopes across all age groups
e
Trab.BV/TV reported, not Trab.vBMD
f
Periosteal diameter is reported, not TA
g
Endocortical perimeter is reported, not MA
h
Cortical thickness is reported, not CA
i
BMC/estimated volume
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