Biomedical Engineering Reference
In-Depth Information
Table 2
(continued)
Study
Animal sex,
species (strain)
Age
Protocol
Significant observations regarding
the influence of loading
Conclusion
Hoshi et al.
[ 34 ]
Female,
Mice (ICR)
2-18 months
Wheel running, at ages:
10-30 week—Young
Exercise (YE)
30-50 week—Mature
Exercise (ME)
50-70 week—Old
Exercise (OE)
10-70 week—Life long
Exercise (LE)
Femur
Ultimate force: YE:,ME:,LE:
Cortical thickness: YE:,ME:,
LE:
Bone density: All:
Modest age effect;
old less
responsive
Honda
et al.
[ 36 ]
Male, Rat
(Wistar)
3 months—young
11 months—mature
Jump training, 8 weeks
10 times/day, 5 days/week,
40 cm
BMC: All:
Cortical area, moment
of inertia: All:
No age effect
Buhl et al.
[ 35 ]
Male, Rat
(Fisher 344)
4 months—young
12 months—mature
22 months—old
Squat-like training, 9 weeks
50 times/day, 3 days/week
added weight—65% body
weight
Tibia
Trabecular spacing, BV/TV: O:
Modest age effect;
old more
responsive
: Increases in response to loading, Y Young, IM Immature, M Mature, O Old. [ 1 ] values were adjusted for muscle mass
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