Biomedical Engineering Reference
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Fig. 2 Longitudinal changes in total area (TA), marrow area (MA) and cortical bone area (CA)
of the tibial diaphysis as measured by pQCT at 3- and 6-year follow up (recreated from Fig. 1 of
Lauretani et al. [ 3 ], with permission). Subjects were grouped by decade at baseline scan. These
results indicate that temporal changes differed greatly with decade and between women and men,
not always in the manner indicated by the cross-sectional studies. For example, past age 80,
women had greater rates of increase in total area than men, both sexes had increasing marrow
area, and women appear to have stable bone area while men lost bone area
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