Biomedical Engineering Reference
In-Depth Information
A specific challenge in understanding matrix level alterations in osteoporosis is
based on the uncertainty of defining what comprises an osteoporotic sample. If the
criterion is a BMD measurement, BMD by and itself is not a reliable indicator of
fracture risk. Another approach would be biopsy collection from individuals with
past fracture history and in such circumstances the compounding effects of past
fracture cannot be adjusted easily.
Acknowledgments This material is based upon work supported by the National Science
Foundation under Grant No. 0620061.
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