Biomedical Engineering Reference
In-Depth Information
Table 1
continued
% Change per decade*
Authors
Materials
Method
Study design
Bone
Sex
D_P
D_M
TA
MA
CA
Moment of inertia
e
j
Lauretani [ 3 ]
809 subjects (464 female,
345 male) 21-102 years
pQCT
CS, LNG
Tibia
Female
-
-
0.8
10.4
-2.1
-
Male
-
-
1.2
3.7
0.6
-
a, k
Yuen [ 9 ]
1258 subjects (638 female,
620 male) 20-98 years
pQCT
CS
Tibia
Female
-
-
-
-
-2.7
-1.9
Male
-
-
-
-
-1.4
-1.8
D_P, periosteal diameter; D_M, medullary diameter; TA, total (subperiosteal) area; MA, medullary area; CA, cortical bone area
All results based on cross-sectional (CS) study design, except Lauretani which is mix of cross-sectional and longitudinal (LNG)
*Percent change calculated using slope of regression line (e.g, TA vs. age), multiplied by 10 and divided by overall mean (unless noted otherwise)
Slopes are taken from papers (if reported), or determined by linear regression from data presented in papers
(NS) regression is not statistically significant, p [ 0.05
Femur: 50 % site (mid-shaft); Tibia: approx. 35 % site (mid-distal); section location is given as percent of limb length, relative to the distal end
a
regressions based on mean values for the age groups reported
b
authors computed areas assuming a circular cross-section
c
section modulus was reported
d
study included six subjects \20 yrs age; these are excluded here
e
from Table 3 of paper
f
estimated from Fig. 2 of paper
g
cortical thickness index is reported, not cortical area
h
Russo (2003, 2006) and Lauretani (2008) report data from same study (InCHIANTI), but Laurentani includes longitudinal data
i
density-weighted moment of inertia reported
j
from Table 4 of paper, recalculated based on estd. overall means
k
Yuen reports slopes for \60 and [60 years in Table 4 of paper; values shown here are computed from slopes across all age groups
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