Biomedical Engineering Reference
In-Depth Information
The resultant complexes have well-defined helical superstructures composed of
two polysaccharide strands and one polynucleotide strand. This unique property
of b-1,3-glucans has made it possible to utilize these polysaccharides as oligo-
DNA carriers. Especially, it was possible to deliver the polynucleotides into the
APCs selectively without using modified SPG because of the presence of a b-1,3-
receptor, dectin-1, on these cells. These findings indicate that b-1,3-glucans are
very attractive and useful materials in biotechnology.
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