Biomedical Engineering Reference
In-Depth Information
41. Chapman, P.B.
Improved survival with vemurafenib in melanoma
with BRAF V600E mutation.
et al.
N Engl J Med
364, 2507-2516 (2011).
42. Nazarian, R.,
Melanomas acquire resistance to B-RAF(V600E)
inhibition by RTK or N-RAS upregulation.
et al.
Nature
468
, 973-977
(2010).
43. ZELBORAF TM (vemurafenib) label: http://www.accessdata.fda.gov/
drugsatfda_docs/label/2011/202429s000lbl.pdf.
44. Tarceva (erlotinib) Label: http://www.accessdata.fda.gov/drugsatfda_
docs/label/2010/021743s14s16lbl.pdf.
45. Lynch, T.J.,
Activating mutations in the epidermal growth factor
receptor underlying responsiveness of non-small-cell lung cancer to
gefitinib.
et al.
, 2129-2139 (2004).
46. Rosell, R., Viteri, S., Molina, M.A., Benlloch, S., and Taron, M. Epidermal
growth factor receptor tyrosine kinase inhibitors as first-line treatment
in advanced nonsmall-cell lung cancer.
N Engl J Med
350
Curr Opin Oncol
22
, 112-120
(2010).
47. Dahabreh, I.J.,
Somatic EGFR mutation and gene copy gain as
predictive biomarkers for response to tyrosine kinase inhibitors in
non-small cell lung cancer.
et al.
Clin Cancer Res
16
, 291-303 (2010).
48. Keedy, V.L.,
American society of clinical oncology provisional
clinical opinion: epidermal growth factor receptor (EGFR) mutation
testing for patients With advanced non-small-cell lung cancer
considering first-line EGFR tyrosine kinase inhibitor therapy.
et al.
J Clin
, 2121-2127 (2011).
49. Erbitux (cetuximab) Lablel: http://www.accessdata.fda.gov/
drugsatfda_docs/label/2009/125084s168lbl.pdf.
50. Wong, S.F. Cetuximab: an epidermal growth factor receptor monoclonal
antibody for the treatment of colorectal cancer.
Oncol
22
Clin Ther
27
, 684-694
(2005).
51. Goldberg, R.M. Cetuximab.
, S10-1 (2005).
52. Vectibix (panitumumab) Label: http://www.accessdata.fda.gov/
drugsatfda_docs/label/2009/125147s080lbl.pdf.
53. Moroni, M.,
Nat Rev Drug Discov
Suppl
Gene copy number for epidermal growth factor
receptor (EGFR) and clinical response to antiEGFR treatment in
colorectal cancer: a cohort study.
et al.
Lancet Oncol
6
, 279-286 (2005).
54. Chung, K.Y.,
Cetuximab shows activity in colorectal cancer patients
with tumors that do not express the epidermal growth factor receptor
by immunohistochemistry.
et al.
J Clin Oncol
23
, 1803-1810 (2005).
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