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in dihydropyrimidine dehydrogenase detected in cancer patients with
5-fluorouracil-related side effects.
, 22: 498.
21. Hormozian, F., Schmitt, J.G., Sagulenko, E., Schwab, M., and Savelyeva, L.
(2007): FRA1E common fragile site breaks map within a 370kilobase
pair region and disrupt the dihydropyrimidine dehydrogenase gene
(DPYD).
Hum. Mutat.
, 246: 82-91.
22. Johnson, M.R., Yan, J., Shao, L., Albin, N., and Diasio, R.B. (1997):
Semi-automated radioassay for determination of dihydropyrimidine
dehydrogenase (DPD) activity. Screening cancer patients for DPD
deficiency, a condition associated with 5-fluorouracil toxicity.
Cancer Lett.
J.
, 696: 183-191.
23. Kleibl, Z., Fidlerova, J., Kleiblova, P., Kormunda, S., Bilek, M., Bouskova,
K., Sevcik, J., and Novotny, J. (2009): Influence of dihydropyrimidine
dehydrogenase gene (DPYD) coding sequence variants on the
development of fluoropyrimidine-related toxicity in patients
with high-grade toxicity and patients with excellent tolerance of
fluoropyrimidine-based chemotherapy.
Chromatogr. B Biomed. Sci. Appl.
, 56: 303-316.
24. Loganayagam, A., Arenas-Hernandez, M., Fairbanks, L., Ross, P.,
Sanderson, J.D., and Marinaki, A.M. (2010): The contribution of
deleterious DPYD gene sequence variants to fluoropyrimidine toxicity
in British cancer patients.
Neoplasma
Cancer Chemother. Pharmacol.
, 65: 403-
406.
25. Lohkamp, B., Voevodskaya, N., Lindqvist, Y., and Dobritzsch, D. (2010):
Insights into the mechanism of dihydropyrimidine dehydrogenase
from site-directed mutagenesis targeting the active site loop and redox
cofactor coordination.
, 1804: 2198-2206.
26. Maekawa, K., Saeki, M., Saito, Y., Ozawa, S., Kurose, K., Kaniwa,
N., Kawamoto, M., Kamatani, N., Kato, K., Hamaguchi, T., Yamada,
Y., Shirao, K., Shimada, Y., Muto, M., Doi, T., Ohtsu, A., Yoshida, T.,
Matsumura, Y., Saijo, N., and Sawada, J. (2007): Genetic variations and
haplotype structures of the DPYD gene encoding dihydropyrimidine
dehydrogenase in Japanese and their ethnic differences.
Biochim. Biophys. Acta
J. Hum. Genet.
,
52: 804-819.
27. Magne, N., Etienne-Grimaldi, M.C., Cals, L., Renee, N., Formento,
J.L., Francoual, M., and Milano, G. (2007): Dihydropyrimidine
dehydrogenase activity and the IVS14+1G>A mutation in patients
developing 5FU-related toxicity.
, 64: 237-240.
28. Maring, J.G., van Kuilenburg, A.B.P., Haasjes, J., Piersma, H., Groen, H.J.M.,
Uges, D.R.A., van Gennip, A.H., and de Vries, E.G.E. (2002): Reduced 5-FU
Br. J. Clin. Pharmacol.
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