Biomedical Engineering Reference
In-Depth Information
Drug
Class/
mechanisms of action
Indications
Dose
Major side effects
Anastrozole
(Arimidex
®
)
AI:
A selective non-steroidal AI
Adjuvant:
Postmenopausal women with
hormone-receptor positive early
breast cancer
Advanced/Metastatic:
- First-line treatment of
postmenopausal women with
hormone receptor-positive or
hormone receptor unknown locally
advanced or metastatic
- Second-line treatment in
postmenopausal women with
disease progression following
tamoxifen therapy
1 mg once
daily
-Decrease in bone
mineral density
-Fatigue / asthenia
- Hot flushes
-Arthralgia
- Musculoskeletal pain
(
Continued
)
