Is Thyroid Hormone Signaling Relevant for Vertebrate Embryogenesis? - Current Topics in Developmental Biology - page 377

A

Impaired TH signaling
has developmental
effect

Morphogenesis is
controlled by TH
signaling

TH signaling is
crucial for
homeostasis

Decline in TH
signaling

Whole body

Cleavage Embryogenesis Metamorphosis Adult life Senescence

B

Tr a

T 4

TR b

T 3

NF1 NF10 NF24 NF37 NF41 NF45 NF46 NF48

C

Dio1

T 4

T 3

Dio2

Dio3

NF1 NF10 NF24 NF37 NF41 NF45 NF46 NF48