Biology Reference
In-Depth Information
A
0
206,775
413,550
620,325
827,100
1,033,875
0
206,775
413,550
620,325
827,100
1,033,875
RefSeq_genes
Ensembl_genes
XenBase_genes
Gurdon_est
B
0
885,256
1,770,513
2,655,769
3,541,026
4,426,282
1,768,744
1,874,869
1,980,993
2,087,118
2,193,242
2,299,367
TR
b
RefSeq_genes
Ensembl_genes
XenBase_genes
Gurdon_est
Probesets
C
0
190,375
380,750
571,126
761,501
951,876
0
190,375
380,750
571,126
761,501
951,876
XenBase_genes
Probesets
Defunct_probesets
Figure 10.2 Limits of the current gene annotation and microarray design. (A) Compar-
ison gene annotations from different sources. The first three tracks represent gene
models described in RefSeq, Ensembl, and XenBase. The orientation of each gene model
is indicated by arrows. The fourth track corresponds to the EST clusters computed at the
Gurdon institute (available on the XenBase website). The scaffold shown is scaffold_448.
(B) Affymetrix probesets located around the TR
b
locus (scaffold_26). The four top tracks
correspond to the same datasets as in A. The last track represents the genomic region
spanned by the Affymetrix X. tropicalis transcriptome microarrays probesets, curated
from defunct probesets. Note that there are no probeset associated with TR
b
. Thus,
