Biology Reference
In-Depth Information
D. melanogaster
Chr.
~130 kb
(2)
miR-1
miR-133
M. musculus
~9.4 kb
(2)
miR-1a-1
miR-133a-2
~2.5 kb
(18)
miR-1a-2
miR-133a-1
~3.7 kb
(1)
miR-206
miR-133b
~1.3 kb
(18)
miR-143
miR-145
miR-
208a
(14)
myh6
miR-
208b
myh7
(14)
miR-
499
(2)
myh7a
Figure 3.1
Genomic organization of muscle miRNAs in flies and mice. In both flies
and mice, members of the
miR-1
and
miR-133
are clustered together. Additional mouse
miRNAs are also clustered, including
miR-143
and
miR-145
. Other muscle miRNAs,
like
miR-208a
,
miR-208b
, and
miR-499
, are located within the introns of myosin genes.
Chromosomal locations are indicated in parentheses.
