Biomedical Engineering Reference
In-Depth Information
FIGURE 1.5: Illustrative simulations of the biological role of chemotaxis.
In a 300 100-site domain , an initially round cell of 30 sites of diame-
ter is placed; see black individual. The target measures of the simulated cell,
A surface
C
and A perimeter
C
, coincide to its initial dimensions. surface
C = 50 site 2
and perimete C = 0:2 site 1 . A point source of a chemical, that evolves satis-
fying Equation (1.15), is applied in x = (300; 150). If che C = 10 M 1 , the
cell moves in the directions of higher morphogen concentrations, displaying
a persistent directional migration. If che C = 0 M 1 , the motion of cells is
uncorrelated from the chemical field. Finally, if che C = 10 M 1 , the cell
moves in the opposite direction w.r.t. the chemical gradient. Isolines indicate
chemical levels.
motion, almost remaining in the initial position, since it is not affected by the
chemical field.
 
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